מאמרים באנגלית על קריאטין

[blinki]

אני צריך כמה שיותר מאמרים באנגלית על קריאטין שבהם כתוב שקריאטין לא מזיק, מומלץ שזה יהיה מחקר מדעי מוכח.
ואם במקרה כתוב גם על המוצר green magnitude אז אדרבה.
תודה מראש

[benwin21]

הנה הרבה מאמרים על קריטאין

http://www.:):):):):):):):):):):):):):):):):)/fun/bbin...?page=Creatine

הנה מה שביקשת על green
http://www.:):):):):):):):):):):):):):):):):)/store/clabs/mag.html

[blinki]

אם אפשר אז לא מאתרים בעלי אינטרס כלכלי.
אבל תודה

[Nicolas]

מזה green?
אבנתי שזה קשור לקריאטין אכשהו

[m0she]

Mol Cell Biochem. 2003 Feb;244(1-2):95-104.

Long-term creatine supplementation does not significantly affect clinical markers of health in athletes.

Creatine has been reported to be an effective ergogenic aid for athletes. However, concerns have been raised regarding the long-term safety of creatine supplementation. This study examined the effects of long-term creatine supplementation on a 69-item panel of serum, whole blood, and urinary markers of clinical health status in athletes. Over a 21-month period, 98 Division IA college football players were administered in an open label manner creatine or non-creatine containing supplements following training sessions. Subjects who ingested creatine were administered 15.75 g/day of creatine monohydrate for 5 days and an average of 5 g/day thereafter in 5-10 g/day doses. Fasting blood and 24-h urine samples were collected at 0, 1, 1.5, 4, 6, 10, 12, 17, and 21 months of training. A comprehensive quantitative clinical chemistry panel was determined on serum and whole blood samples (metabolic markers, muscle and liver enzymes, electrolytes, lipid profiles, hematological markers, and lymphocytes). In addition, urine samples were quantitatively and qualitative analyzed to assess clinical status and renal function. At the end of the study, subjects were categorized into groups that did not take creatine (n = 44) and subjects who took creatine for 0-6 months (mean 4.4 +/- 1.8 months, n = 12), 7-12 months (mean 9.3 +/- 2.0 months, n = 25), and 12-21 months (mean 19.3 +/- 2.4 months, n = 17). Baseline and the subjects' final blood and urine samples were analyzed by MANOVA and 2 x 2 repeated measures ANOVA univariate tests. MANOVA revealed no significant differences (p = 0.51) among groups in the 54-item panel of quantitative blood and urine markers assessed. Univariate analysis revealed no clinically significant interactions among groups in markers of clinical status. In addition, no apparent differences were observed among groups in the 15-item panel of qualitative urine markers. Results indicate that long-term creatine supplementation (up to 21-months) does not appear to adversely effect markers of health status in athletes undergoing intense training in comparison to athletes who do not take creatine.

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1: J Sports Med Phys Fitness. 2004 Dec;44(4):411-6.

Is the use of oral creatine supplementation safe?
School of Sports Medicine, University of Trieste, Trieste, Italy.

This review focuses on the potential side effects caused by oral creatine supplementation on gastrointestinal, cardiovascular, musculoskeletal, renal and liver functions. No strong evidence linking creatine supplementation to deterioration of these functions has been found. In fact, most reports on side effects, such as muscle cramping, gastrointestinal symptoms, changes in renal and hepatic laboratory values, remain anecdotal because the case studies do not represent well-controlled trials, so no causal relationship between creatine supplementation and these side-effects has yet been established. The only documented side effect is an increase in body mass. Furthermore, a possibly unexpected outcome related to creatine monohydrate ingestion is the amount of contaminants present that may be generated during the industrial production. Recently, controlled studies made to integrate the existing knowledge based on anecdotal reports on the side effects of creatine have indicated that, in healthy subjects, oral supplementation with creatine, even with long-term dosage, may be considered an effective and safe ergogenic aid. However, athletes should be educated as to proper dosing or to take creatine under medical supervision

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1: Eur J Nutr. 2005 Jun;44(4):255-61. Epub 2004 Aug 11.
Risk assessment of the potential side effects of long-term creatine supplementation in team sport athletes.

Lipids and Cardiovascular Epidemiology, Unit Institut Municipal d'Investigació Mèdica, IMIM, c/Doctor Aiguader 80, 08003, Barcelona, Spain. hschroeder@imim.es


BACKGROUND: Use of creatine has become widespread among sportsmen and women, although there are no conclusive evidences concerning possible health risks of long-term creatine supplementation. THE AIM OF THE STUDY: To investigate long-term effects of creatine monohydrate supplementation on clinical parameters related to health. METHODS: Eighteen professional basketball players of the first Spanish Basketball League participated in the present longitudinal study. The subjects were ingesting 5 g creatine monohydrate daily during three competition seasons. Blood was collected in the morning after an overnight fast, five times during each of the three official competition seasons of the first National Basketball League (September 1999-June 2000, September 2000-June 2001 and September 2001-June 2002) and the European League. Standard clinical examination was performed for 16 blood chemistries. RESULTS: The plasma concentrations of all clinical parameters did not alter significantly during the analyzed time frames of creatine supplementation. All of these parameters were, with the exception of creatinine and creatine kinase, within their respective clinical ranges at all time points. CONCLUSION: Our data shows that low-dose supplementation with creatine monohydrate did not produce laboratory abnormalities for the majority of the parameters tested.